Wellbutrin, the brand name for bupropion, is primarily an antidepressant but can also been used off label to treat Attention Deficit Hyperactivity Disorder (ADHD). Wellbutrin primarily affects the neurotransmitters noradrenaline (norepinephrine) and What It's Like to Take Contrave for Weight Loss GoodRx Naltrexone vs. Suboxone How are They Different? Bupropion: How It Works, How to Take It, and Side Effects